RAO: Amputation/reintervention free by anatomic high-risk: distal anastomosis is femoral/popliteal vs more distal
(open surgery placebo patients only)

The FREQ Procedure

Frequency
Row Pct
Table of popout by raoc
popout(Distal
anastamosis
is popliteal)
raoc(Amputation or Revision)
0=Censored 1=Event Total
0=No
307
60.79
198
39.21
505
1=Yes
228
68.47
105
31.53
333
Total
535
303
838


Statistics for Table of popout by raoc

Statistic DF Value Prob
Chi-Square 1 5.1227 0.0236
Likelihood Ratio Chi-Square 1 5.1635 0.0231
Continuity Adj. Chi-Square 1 4.7955 0.0285
Mantel-Haenszel Chi-Square 1 5.1166 0.0237
Phi Coefficient -0.0782
Contingency Coefficient 0.0779
Cramer's V -0.0782

Fisher's Exact Test
Cell (1,1) Frequency (F) 307
Left-sided Pr <= F 0.0140
Right-sided Pr >= F 0.9905
Table Probability (P) 0.0045
Two-sided Pr <= P 0.0275


Sample Size = 838

RAO: Amputation/reintervention free by anatomic high-risk: distal anastomosis is femoral/popliteal vs more distal
(open surgery placebo patients only)

The LIFETEST Procedure

Summary of the Number of Censored and Uncensored Values
Stratum popout Total Failed Censored Percent
Censored
1 0=No 505 198 307 60.79
2 1=Yes 333 105 228 68.47
Total 838 303 535 63.84

The LIFETEST Procedure

Plot of SDF vs raod

The LIFETEST Procedure


Testing Homogeneity of Survival Curves for raod over Strata

Rank Statistics
popout Log-Rank Wilcoxon
0=No 17.345 9235.0
1=Yes -17.345 -9235.0

Covariance Matrix for the
Log-Rank Statistics
popout 0=No 1=Yes
0=No 72.6712 -72.6712
1=Yes -72.6712 72.6712

Covariance Matrix for the
Wilcoxon Statistics
popout 0=No 1=Yes
0=No 30463858 -3.046E7
1=Yes -3.046E7 30463858

Test of Equality over Strata
Test Chi-Square DF Pr >
Chi-Square
Log-Rank 4.1397 1 0.0419
Wilcoxon 2.7996 1 0.0943
-2Log(LR) 5.0712 1 0.0243

RAO: Amputation/reintervention free by anatomic high-risk: distal anastomosis is femoral/popliteal vs more distal
(open surgery placebo patients only)

The PHREG Procedure

Model Information
Data Set SVS.COMBO
Dependent Variable raod Days to Revision or Amputation
Censoring Variable raoc Amputation or Revision
Censoring Value(s) 0
Ties Handling BRESLOW

Number of Observations Read
Number of Observations Used
838
838

Class Level Information
Class Value Design
Variables
popout 0=No 0
1=Yes 1

Summary of the Number of Event and Censored
Values
Total Event Censored Percent
Censored
838 303 535 63.84

Convergence Status
Convergence criterion (GCONV=1E-8) satisfied.

Model Fit Statistics
Criterion Without
Covariates
With
Covariates
-2 LOG L 3899.810 3895.610
AIC 3899.810 3897.610
SBC 3899.810 3901.323

Testing Global Null Hypothesis: BETA=0
Test Chi-Square DF Pr > ChiSq
Likelihood Ratio 4.2001 1 0.0404
Score 4.1258 1 0.0422
Wald 4.1051 1 0.0428

Type 3 Tests
Effect DF Wald
Chi-Square
Pr > ChiSq
popout 1 4.1051 0.0428

Analysis of Maximum Likelihood Estimates
Parameter DF Parameter
Estimate
Standard
Error
Chi-Square Pr > ChiSq Hazard
Ratio
95% Hazard Ratio Confidence
Limits
Label
popout 1=Yes 1 -0.24464 0.12075 4.1051 0.0428 0.783 0.618 0.992 Distal anastamosis is popliteal 1=Yes

RAO: Amputation/reintervention free by anatomic high-risk: distal anastomosis is femoral/popliteal vs more distal title2 kaplan-meier survival estimates with 95% confidence intervals

Obs popout raod Failed Left Survival minus plus
1 0=No 354.000 195 244 0.5833 53.8148 62.8375
2 1=Yes 364.000 105 174 0.6593 60.5818 71.2707

criticallimb.org , from SVS and UCSF